News

27.11.2024 wednesday

at the last meeting of the Chemistry Committee of the Polish Aacademy of Sciences I was elected chairman of the Science Commission. It’s time to roll up sleeves – we are open to all initiatives!
22.11.2023 wednesday

The good news of today is that our grant application with Prof. Ji Li for the Polish-Chinese cooperation (within the Sheng competition) has been qualified for financing!
24.04.2023 monday

Today I had the pleasure of participating in the ceremony of conferring the honorary doctorate of the Warsaw University of Technology on my friend from school, Professor Andrzej Strójwąs. It was an exciting journey back in time. Congratulations Andrzej!
20.02.2023 monday

Today, the first in the new term meeting of the Scientific Council of the Center for Molecular and Macromolecular Research of the Polish Academy of Sciences (CBMiM PAN) took place, at which I was unanimously elected Chairman of the Council. I would like to thank all members for their trust and election to this honorable position. I will do my best to fulfill the hopes placed on my skills.
01.02.2023 wednesday

Dear Colleagues, A plethora of applications of chemical and biochemical molecules, ranging from the medical use of small molecule drugs through complicated bio-vaccines to material design, cannot be achieved without a deep understanding of the processes involved in their preparation and action. This can be achieved nowadays via both experimental as well as theoretical studies. In this Special Issue, we would like to focus on the latest developments in the area of studying (bio)reaction mechanisms. Consequently, we look forward to collecting original research reports, as well as reviews of recent progress and perspectives from experts in the field. Prof. Dr. Piotr Paneth Guest Editor
31.05.2022 tuesday

As a part of the ISI-Isotopes2022 conference, one of the sessions was dedicated to my 70th birthday. My deepest thanks go to everyone who contributed to the organization of this touching and unforgettable event.
30.01.2022 sunday

as part of the International Journal of Molecular Sciences, I am preparing a special collection entitled “State-of-the-Art Biochemistry in Poland”. I invite interested persons to visit the website https://www.mdpi.com/journal/ijms/special_issues/Biochemistry_PL or contact me directly. volume_up content_copy share star_border  
21.10.2021 thursday

another special issue which I am co-editing, this time at the invitation of Professor Marek Cypryk, is dedicated to the scientific achievements of Professor Donald Truhlar. More details at https://www.mdpi.com/journal/molecules/special_issues/Donald_Truhlar Please, join us!

Curriculum vitae

Professor 1996; President of the Republic of Poland
D.Sc. (habilitation) 1989; Isotope effects on kinetically complex reactions; Department of Chemistry, Technical University of Łódź, Poland
Ph.D. 1984 (with honors); Oxygen and sulfur kinetic isotope effects on thermal isomerization of bis(5,5-dimethyl-1,3,2,-dioxaphosphorinanyl); advisor prof. dr. W Reimschüssel; Department of Chemistry, Technical University of Łódź, Poland
M.S. 1976 (with honors); Oxygen kinetic isotope effect on isomerization of monothiopyrophosphates; advisor prof. dr. W Reimschüssel; Department of Chemistry, Technical University of Łódź, Poland
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Publications

  • “Novel toxicity-associated metabolic pathways of benzotriazole UV stabilizers by cytochrome P450: mechanism-directed analysis” Cheng Shiyang, Su Lijing, Han Ye, Jin Lingmin, Ma Juchen Kong Chuiyuan, Zhang Shubin, Huang Jiawei, Liu Chunsheng, Paneth Piotr, Ji Li, Environment International 205, 109887 (2025)
  • „Mercury Contamination in Polar Fish: Bioaccumulation and Trophic Transfer in Notothenia coriiceps from Admiralty Bay, maritime Antarctic” Kacper Jurczyk, Dominika Saniewska, Mariusz Sapota, Piotr Paneth, Michał Saniewski, Marine Chemistry 273, 104564 (2025)
  • “Dermatophyte-selective imidazole-thiosemicarbazides: potent in vitro activity against Trichophyton and Microsporum with no anti-Candida effect” Agata Paneth, Katarzyna Dzitko, Adrian Bekier, Nazar Trotsko, Katarzyna Suśniak, Anita Ciesielska, Piotr Paneth Int. J. Mol. Sci. 26, 9437 (2025)
  • “Alterations of 13C and 15N Isotope Abundance as a Potential Biomarker for Tumor Biology and Risk Factor of Cervical Lymph Node Metastases in Oral Squamous Cell Carcinoma” Katarzyna Bogusiak, Piotr Paneth, Józef Kobos, Marcin Kozakiewicz, Cancers, 17, 3047 (2025). Preprints 11 August 2025 DOI: 10.20944/preprints202508.0702.v1
  • “A new paradigm for drug deuteration based on binding isotope effects” Agata Paneth, Piotr Paneth  Authorea July 17, 2025. DOI: 22541/au.175275014.42014912/v1
  • “Low-Cost Periodic Calculations of Metal-Organic Frameworks: A GFN1-xTB Perspective” Mateusz Pokora, Jakub Goclon, Johannes Margraf, Chiara Panosetti, Artem Samtsevych, Piotr Paneth, ChemPhysChem 26, e202500081 (2025)
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ISOEFF

[:pl]Program Isoeff służy do wyznaczania wartości efektów izotopowych, zgodnie z równaniem Bigeleisena, na podstawie wyników obliczeń kwantowo-mechanicznych. Wykorzystane mogą być wyniki uzyskane za pomocą pakietów: Gaussian, Gamess, Charmm i Mopac. Isoeff pozwala również na badanie wpływu niewielkich zmian wartości poszczególnych elementów macierzy Hessian na wartość efektu izotopowego.
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Current support

Current support / Personal
  • NCN 2023/48/Q/ST10/00247 “Study on the dehalogenation mechanisms of typical halogenated organic pollutants by F430 coenzyme purified from methanogenic bacteria” (2024-2027) Sheng (Polish – Chinese collaboration grant) – Polish PI
  • CheMatSustain, Project 101137990 “Implementing innovative methods for safety and sustainability assessments of chemicals and materials particularly at nano level in the European Union” (2024-2029) – team member
  • NCN, M.ERA-NET ”Hybrid ELectrosynthesis of Value-Added chemicals (HELVA)” (2023-2026) – local coPI
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Innovations

International patents
  • “N-Triazynylammonium salts, a method of preparation and uses thereof” European submission EPO nr. 10195135.8-2101 from 07.03.2011 with priority PL/14.07.10/PLA 39183210, European patent awarded: 2407460B1 17.07.2013
Polish patents
  • „Sposób autentykacji kawy” Ewelina Kosiacka, Piotr Paneth, pending patent nr P.396939 of 10.11.2011, awarded: PAT.220057 16.12.2014
  • “Pochodne 1,2,4-triazolo-5-tionu oraz ich zastosowanie” Tomasz Frączek, Agata Siwek, Piotr Paneth pending patent P.401956 of 10.12.2012, published PAT.221213 on 23.6.2014
  • „Nowa pochodna 1,4-dipodstawionego tiosemikarbazydu, sposób jej wytwarzania oraz inhibicja bakteryjnej topoizomerazy IV” A. Siwek, P. Paneth, P. Stączek, J. Stefańska, pending patent nr P.390774 z dnia 20.03.2010, awarded: PAT.212639 19.04.2012
  • “Sposób przygotowania próbki chlorku srebra przeznaczonej do badania składu izotopowego chloru w spektrometrach mas z jonizacją FAB lub SIMS” R. Kamiński, P. Paneth, pending patent nr P.388338 z dnia 22.06.2009)  awarded: PAT.212330 02.04.2012
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Courses based on research (RBL)

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  • 2015: w ramach zajęć z modelowania molekularnego ze słuchaczami studium doktoranckiego prowadzimy badania preferencyjnego wiązania kationów metali przez centra zagnieżdżone w polimerach.
  • 2008: w ramach laboratorium z chemii obliczeniowej ze studentami 4 roku chemii zbadaliśmy metodami teoretycznymi wpływ mechanizmu reakcji dehalogenacji na wartości kinetycznych efektów izotopowych. Wyniki zostały opublikowane w wydawanym przez Americal Chemical Society czasopiśmie Journal of Chemical Theory and Computations (IF2014 = 5.50):"A DFT study of the kinetic isotope effects on the competing SN2 and E2 reactions between hypochlorite anion and ethyl chloride" A. Pabis, P. Paluch, J. Szala, P. Paneth, J. Chem. Theory Comput. 5, 33-36 (2009)
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