8th ISI conference was weld in Nantes from 3rd to 6th of November. Apart from meeting people working whole life on isotopes (with John Hayes in the picture) a numer of new, important developments have been presented, including application of isotopic ratios in cancer diagnostics (the team from Nantes published their report simultaneously with our Oncotarget paper), diabetic breath test, or clamped isotopes (see pictures).